The natural aging process causes your collagen to break down, taking away facial volume. RADIESSE® wrinkle filler not only instantly restores facial volume to smooth out the signs of aging, it keeps working with your body by stimulating your own natural collagen for long-lasting results in many patients.

What is RADIESSE®?

RADIESSE® wrinkle filler is an injectable implant composed of a synthetically produced substance. The ideal way to achieve wrinkle reduction is by replenishing lost volume. With RADIESSE® wrinkle filler, you welcome back your own natural collagen to smooth out the signs of aging. That's because RADIESSE® wrinkle filler's unique formulation stimulates collagenesis – the production of new collagen – which results in increased volume for natural looking wrinkle correction that may last a year or more in many patients. It's also why more and more cosmetic surgeons, estheticians, and other medical professionals are choosing RADIESSE® wrinkle filler for long-lasting facial rejuvenation.

How is RADIESSE® administered?

RADIESSE® is injected into the skin in a minimally invasive procedure. Injection of the product provides an immediate one-to-one correction of the face wrinkle. The amount of filling or augmentation can be easily placed and controlled for better results. There is no skin sensitivity testing or reconstitution required. Additionally, in a recent clinical study, RADIESSE®, when mixed with an anesthetic called lidocaine, significantly reduced pain during treatment. What that means for you is a safe, FDA-approved approach to significantly more comfortable treatment.

How soon will I see a difference? What kind of results can I expect?

A RADIESSE® treatment delivers immediate correction. Typically only one treatment will give optimal results for most patients, although a touch-up may be required. Over time, the gel is absorbed, and fibroblasts appear. The process of neocollagenesis begins, stimulating the gradual growth of your own collagen. The collagen that forms results in extended correction times and increased patient satisfaction. Results typically last up to a year or more for many patients. The results are long-lasting, but not permanent.

How does it work?

The illustrations below depict the increase in collagen growth post-RADIESSE® treatment. The photo on the left is immediately after the RADIESSE® injection. The photo on the right shows increased collagen production 6 months later. Collagen is represented as the dark orange strands.

What results should I expect?

You can expect soft, natural-looking results that feel like your own tissue. The primary component in a RADIESSE® treatment is identical in composition to the mineral portion of bones and teeth. It contains no human- or animal-derived components, and there is virtually no risk of allergic reaction. A RADIESSE® treatment also does not require sensitivity testing prior to treatment.

What are the common side effects?

The most common side effects following the injection of RADIESSE® wrinkle filler include slight bruising, redness and swelling. These side effects are generally mild and only last for a short time.

What areas can be treated with RADIESSE®?

Treatment areas for RADIESSE® include

• smile lines (the lines and creases that run from the side of the nose to the corner of the mouth),
• marionette lines (the lines and creases that run downward from the corners of the mouth that can make you look like you're frowning, even when you're not),
• oral commissure (the corners of the mouth that take on a downturned appearance), and
• pre-jowl (the area on either side of the chin).

Here are some typical before-and-after photos.

	Smile Lines on Woman Before treatment
	After treatment
	Smile Lines on Man Before Treatment
	After treatment
	Marionette Lines Before Treatment
	After Treatment
	Oral Commissures Before Treatment
	After Treatment
	Pre-Jowl Before Treatment
	After Treatment